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ML318

CAS No. : 1610516-67-0

Biological Activity：ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC₅₀ of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC₅₀ of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.

Research Area：Infection

Targets：Antibiotic

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Antibiotics Library;Anti-Pulmonary Fibrosis Compound Library;

Related Small Molecules:Sandramycin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Leucomycin;Vidarabine monohydrate;Nafcillin;Staurosporine;Clotrimazole-d5;SQ109;(R)-Camptothecin-d5;Neomycin sulfate;Framycetin;Colistin sulfate;Pyrantel;L-Lactic acid;SPR741 TFA;Faropenem;Hypericin;Moniliformin sodium salt

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