Aspirin

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Aspirin

CAS No. : 50-78-2

Biological Activity:Aspirin (Acetylsalicylic Acid) is an orally active, potent and irreversible inhibitor of cyclooxygenase COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively. Aspirin induces apoptosis. Aspirin inhibits the activation of NF-κB. Aspirin also inhibits platelet prostaglandin synthetase, and can prevent coronary artery and cerebrovascular thrombosis[2][3][4][5][6].

Research Area:Cancer|Infection|Metabolic Disease|Inflammation/Immunology|Cardiovascular Disease

Targets:Autophagy|NF-κB|p38 MAPK|Mitophagy|Caspase|Apoptosis|Virus Protease|COX

Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Pyroptosis Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Mitochondria-Targeted Compound Library;Transcription Factor-Targeted Library;Food-Sourced Compound Library ;Animal Disease Model Inducer Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Children’s Drug Library;Antidepressant Compound Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Osteogenesis Compound Library;Anti-Aging Natural Product Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:Physalin A;Bomedemstat ditosylate;Akt/NF-κB/JNK-IN-1;SRPIN340;Enpp/Carbonic anhydrase-IN-1;GK563;ZIKV-IN-4;Calpeptin;COX-2/5-LOX-IN-3;Lobetyolin;Icariside F2;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;IKKγ NBD Inhibitory Peptide TFA;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5

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