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Nrf2-ARE/hMAO-B/QR2 modulator 1
Biological Activity：Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC50s of 8.05, 9.83 and 0.57 μM for hMAO-B, NRF2 and QR2. Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated mice hippocampal slices.
Research Area：Neurological Disease
Targets：Keap1-Nrf2|Reactive Oxygen Species|Monoamine Oxidase
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