Topiramate

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Topiramate

CAS No. : 97240-79-4

Biological Activity:Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase[2][3].

Research Area:Neurological Disease

Targets:Calcium Channel|Sodium Channel|Potassium Channel|Carbonic Anhydrase|GABA Receptor|iGluR

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