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FT113

CAS No. : 1630808-89-7

Biological Activity：FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC₅₀ of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC₅₀, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo.

Research Area：Cancer

Targets：Fatty Acid Synthase (FASN)

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Orally Active Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Lipid Metabolism Compound Library ;

Related Small Molecules:UCM05;Pedunculoside;Lycorine;Orlistat;HS80;Cerulenin;Praeruptorin B;Albaspidin AP;Pseudoprotodioscin;TVB-3664;Leelamine-d4 hydrochloride;Leelamine hydrochloride;FASN-IN-4;BI 99179;Fatostatin hydrobromide;Anti-Mouse Fas Ligand Antibody;FASN-IN-1;Dihydrocurcumin;Agrimol B;PF429242 dihydrochloride;FGH10019;FASN-IN-3;trans-C75;GSK2194069;Betulin;trans-Chalcone;TVB-3166

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