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5-Iodotubercidin
CAS No. : 24386-93-4
Biological Activity:5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin[2][3].
Research Area:Cancer
Targets:Adenosine Kinase
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;Anti-Cancer Compound Library;Nucleotide Compound Library;Targeted Diversity Library;
Related Small Molecules:AK-IN-1;ABT-702 dihydrochloride;GP3269
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