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LSD1-IN-20
CAS No. : 1239589-91-3
Biological Activity:LSD1-IN-20 (compound 1) is a potent dual non-covalent LSD1/G9a inhibitor, with Ki values of 0.44 and 0.68 μM, respectively. LSD1-IN-20 shows antiproliferative activity in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with IC50 (72 h) of 0.51 and 1.60 μM, respectively.
Research Area:Cancer
Targets:Histone Methyltransferase|Histone Demethylase
Related Small Molecules:Bomedemstat ditosylate;EEDi-5285;EZH2-IN-2;BIX-01294;LSD1/ER-IN-1;PBIT;JQKD82;SGC707;(S)-HH2853;G9a-IN-1;UNC4976;MS1943;KDOAM-25 citrate;OTS186935 hydrochloride;GSK-J1 lithium salt;S2116;MS8815;(R)-HH2853;EPZ020411;Furamidine dihydrochloride;EZH2-IN-12;UNC0642;MU1656;Chaetocin;UNC0646;UNC0224;MRK-740
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