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UMI-77
CAS No. : 518303-20-3
Biological Activity：UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
Research Area：Cancer
Targets：Bcl-2 Family
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:BI-3812;Pyridoclax;PUMA BH3 TFA;Dehydrocorydaline;Bufarenogin;Murizatoclax;Obatoclax;CYD-2-11;BM 957;(S)-Gossypol (acetic acid);A-385358;Mcl-1 inhibitor 6;S55746;Anticancer agent 63;MCL-1/BCL-2-IN-2;Anticancer agent 65;(E)-Ferulic acid-d3;Bcl-2-IN-8;S65487 hydrochloride;PI-1840;MIK665;WEHI-539;Bax activator-1;UBX1325;Mcl-1 inhibitor 3;Maritoclax;ABT 737-d8
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