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JW67
CAS No. : 442644-28-2
Biological Activity：JW67 inhibits the canonical Wnt signaling with an IC50 of 1.17μM. JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth.
Research Area：Cancer
Targets：Wnt
Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Cytoskeleton Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Wnt/β-catenin agonist 1;ARUK3001185;Gallocyanine chloride;Fz7-21;Foxy-5 TFA;Wnt/β-catenin agonist 4;JW74;IQ 1;Heparan Sulfate;ETC-159;Laduviglusib (GMP);KY-05009;HLY78;Wnt-C59;Wogonin;NCB-0846;KY-02327;Echinacoside;IWP-4;Triptonide;Prodigiosin;BML-284 hydrochloride;Astragaloside I;β-catenin-IN-3;NLS-StAx-h;FzM1.8;KY19382;NSC668036
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