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APJ receptor agonist 1
CAS No. : 2287153-38-0
Biological Activity：APJ receptor agonist 1, a biphenyl acid derivative, is a potent APJ receptor (APJ-R) agonist (EC50s 0.093 and 0.12 nM for human and rat APJ-R, respectively). APJ receptor agonist 1 displays in vitro potency to apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 has the potential for the research of heart failure.
Research Area：Cardiovascular Disease
Targets：Apelin Receptor (APJ)
Related Small Molecules:ML221;Apelin-13 TFA;ML233;[Pyr1]-Apelin-13;APJ receptor agonist 5;ELA-11(human) TFA;NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal);AM-8123;Elabela(19-32) TFA;MM 07;APJ receptor agonist 4;ELA-32(human) TFA;Azelaprag;ELA-21 (human);APJ receptor agonist 6;MM 54;CMF019;NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal);Apelin agonist 1;APJ receptor agonist 3
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