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SC-43
CAS No. : 1400989-25-4
Biological Activity：SC-43, a Sorafenib derivative, is a potent and orally active SHP-1 (PTPN6) agonist. SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis. SC-43 has anti-fibrotic and anticancer effects[2].
Research Area：Cancer
Targets：STAT|Phosphatase|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Differentiation Inducing Compound Library;Orally Active Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Phosphatase Inhibitor Library;Anti-Obesity Compound Library;Transcription Factor-Targeted Library;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;GNF362;Cirsilineol;Ecteinascidin 770;MDM2-p53-IN-15;Ochromycinone;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Uralenol
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