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KN-62
CAS No. : 127191-97-3
Biological Activity：KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.
Research Area：Metabolic Disease|Cancer
Targets：CaMK|P2X Receptor
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Related Small Molecules:DB0614;Gefapixant citrate;JNJ-47965567;AF-353;MLCK inhibitor peptide 18;Calmidazolium chloride;Oxatomide;AZ10606120 dihydrochloride;Rimacalib;Taspine;A-317491;CaMKII-IN-1;NF449 octasodium;A-804598;Syntide 2 TFA;Ph-HTBA;P2X receptor-1;PROTAC eEF2K degrader-1;Aurintricarboxylic acid;Minodronic acid;NF023 hexasodium;A 438079 hydrochloride;Autocamtide-2-related inhibitory peptide, myristoylated;Opiranserin;GW791343 dihydrochloride
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