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TDI-10229
Biological Activity：TDI-10229 is a potent and orally bioavailable inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50 of 195 nM) and exhibits mouse pharmacokinetic properties sufficient to warrant its use as an in vivo tool compound[2].
Research Area：Others
Targets：Adenylate Cyclase
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Orally Active Compound Library;
Related Small Molecules:NKY80;Fipexide;CB-7921220;Angiopeptin;Mant-GTPγS;SKF-83566;Forskolin;Lysipressin acetate;TIP 39, Tuberoinfundibular Neuropeptide;Small Cardioactive Peptide B (SCPB);Cholera toxin;SQ22536;AC1-IN-1;Adenylyl cyclase type 2 agonist-1;TDI-11861;ST034307;LRE1;NKH477;[DPro10] Dynorphin A (1-11), porcine;Forskolin (GMP);[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat;KH7;NB001
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Structurally and synthetically diverse biologically active compounds；
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