For research use only. We do not sell to patients.
PIM1-IN-1
CAS No. : 1417630-95-5
Biological Activity：PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity.
Research Area：Cancer
Targets：Pim
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:GDC-0339;Pim-1 kinase inhibitor 1;(1S,3R,5R)-PIM447 dihydrochloride;PIM1-IN-3;TCS-PIM-1-4a;PIM-1/HDAC-IN-1;Pim1/AKK1-IN-1;AZD1208 hydrochloride;TP-3654;Pim-1/2 kinase inhibitor 1;Hispidulin;MNK/PIM-IN-1;Pim-1 kinase inhibitor 3;PIM1-IN-4;CK2/ERK8-IN-1;PIM1-IN-6;SEL24-B489;SGI-1776;PIM1-IN-7;CDK6/PIM1-IN-1;CK2/PIM1-IN-1;Uzansertib;CX-6258 hydrochloride;SMI-16a;M-110;PIM-IN-1
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
