Oxypeucedanin

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Oxypeucedanin

CAS No. : 737-52-0

Biological Activity:Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC50 value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation. Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration[2].

Research Area:Cancer|Cardiovascular Disease

Targets:Potassium Channel|Apoptosis

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