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GSK-3685032
CAS No. : 2170137-61-6
Biological Activity：GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition.
Research Area：Cancer
Targets：DNA Methyltransferase
Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Anti-Cancer Compound Library;Reprogramming Compound Library;Anti-Blood Cancer Compound Library;Transcription Factor-Targeted Library;
Related Small Molecules:RSC133;SGI-1027;γ-Oryzanol;Bobcat339;TFMB-(S)-2-HG;Dihydro-5-azacytidine;DC-05;Zebularine;Hinokitiol;2′-Deoxy-5-nitrocytidine;SW155246;DC_517;Lomeguatrib;ZIKV-IN-2;O6BTG-octylglucoside;AA-CW236;DY-46-2;RG108;Psammaplin A;DNMT3A-IN-2;Nanaomycin A;ZIKV-IN-3;5-Azacytidine;CM-579
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