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LX2343
CAS No. : 333745-53-2
Biological Activity：LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
Research Area：Neurological Disease
Targets：Autophagy|Beta-secretase|Amyloid-β|PI3K
Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Neuronal Signaling Compound Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:LY2886721;β-Amyloid (13-27);Umbralisib hydrochloride;Saikosaponin C;Topoisomerase I/II inhibitor 3;β-Amyloid (1-42), (rat/mouse) (TFA);Rigosertib sodium;Tenalisib R Enantiomer;β-Amyloid (12-28) (TFA);BACE1-IN-9;PI3kδ inhibitor 1;BuChE-IN-5;Ginsenoside Rg1;PI3K/VEGFR2-IN-1;MDR-1339;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;β-Amyloid (11-22);PI3Kα-IN-8;20(S)-Ginsenoside Rg3;PI-103 Hydrochloride;β-Amyloid (31-35);IC-87114;PI3K/mTOR Inhibitor-6;Aβ-IN-1;PI3K-IN-10;SF2523
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