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JH-XIV-68-3
CAS No. : 2426628-52-4
Biological Activity：JH-XIV-68-3 is a selective macrocyclic inhibitor of DYRK1A/B. JH-XIV-68-3 displays selectivity for DYRK1A and close family member DYRK1B in biochemical and cellular assays. JH-XIV-68-3 demonstrates antitumor efficacy in head and neck squamous cell carcinoma (HNSCC) cell lines.
Research Area：Cancer
Targets：DYRK
Related Small Molecules:Harmine hydrochloride;T025;ID-8;Dyrk1A-IN-2;GSK-626616;GNF2133 hydrochloride;ARN25068;Haspin-IN-1;LDN-192960 hydrochloride;CLK-IN-T3;GNF4877;DYRKs-IN-2;DYRKs-IN-1 hydrochloride;Protein kinase inhibitors 1 hydrochloride;KH-CB20;Dyrk1A/α-synuclein-IN-2;AZ191;Woodtide;CK2/ERK8-IN-1;DYRK1-IN-1;Dyrk1A-IN-5;ML167;tBID;Dyrk1A-IN-4;Mirk-IN-1;Dyrk1A-IN-1
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