K67

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K67

CAS No. : 2046250-48-8

Biological Activity:K67 specifically inhibits the interaction between Keap1 and S349-phosphorylated p62. K67 prevents p-p62 from blocking the binding of Keap1 and Nrf2. K67 effectively inhibits the proliferation of HCC cultures with high cellular S351-phosphorylated p62 by restoring the ubiquitination and degradation of Nrf2 driven by Keap1.

Research Area:Cancer

Targets:Keap1-Nrf2

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