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Norfluoxetine hydrochloride

CAS No. : 57226-68-3

Biological Activity：Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine. Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor that is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. Norfluoxetine hydrochloride inhibits 5-HT uptake and inhibits CaV3.3 T current (IC50 = 5 μM). Norfluoxetine hydrochloride has anticonvulsant activity^[2]^[3]^[4].

Research Area：Neurological Disease

Targets：Drug Metabolite|5-HT Receptor|Calcium Channel

Related Small Molecules:Nicotinamide N-oxide;F 13714;Benidipine hydrochloride;Mosapride-d5;CaV1.3 antagonist-1;14-Deoxyandrographolide;Nuciferine;(Rac)-MEM 1003;4-Hydroxyphenylbutazone;Ampyrone;Glaucine;Efonidipine hydrochloride monoethanolate;Resveratrol-3-O-sulfate sodium;Renzapride;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Sonidegib metabolite M48;MRS 1523;LY 344864 racemate;Nilvadipine

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