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Vinpocetine-d5
CAS No. : 2734920-39-7
Biological Activity：Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders[2][3].
Research Area：Inflammation/Immunology|Neurological Disease|Cardiovascular Disease|Cancer
Targets：Phosphodiesterase (PDE)|Sodium Channel|IKK
Related Small Molecules:Senazodan hydrochloride;(E/Z)-HA155;Enpp/Carbonic anhydrase-IN-1;Lu AE98134;ATX inhibitor 22;Carbazeran citrate;Zandatrigine;Bay 60-7550;BC11-38;Deltarasin hydrochloride;Glaucine;Veratridine;Brompheniramine-d6 maleate;GX-674;Ziritaxestat;Dibucaine;PS-1145;Udenafil-d7;D159687;ITI-214;NF-κB-IN-1;Sodium Channel inhibitor 2;PDE10-IN-5;3-Deoxyaconitine;20(S)-Ginsenoside Rg3;Resveratrol
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