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Fasudil hydrochloride semihydrate
CAS No. : 186694-02-0
Biological Activity：Fasudil (HA-1077; AT877) hydrochloride semihydrate is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil hydrochloride semihydrate is also a potent Ca2+ channel antagonist and vasodilator[2][3].
Research Area：Cancer
Targets：ROCK|Autophagy|Calcium Channel|PKC|PKA|HIV
Related Small Molecules:[Ala107]MBP(104-118) TFA;Benidipine hydrochloride;PKI 14-22 amide,myristoylated TFA;CaV1.3 antagonist-1;14-Deoxyandrographolide;BJE6-106;HIV-1 TAT (48-60);Myelin Basic Protein;Seletracetam lithium;Staurosporine;HIV-IN-2;PKC-iota inhibitor 1;Triptonine B;(Rac)-MEM 1003;FC131;Glaucine;Efonidipine hydrochloride monoethanolate;Peritassine A;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;Hypericin;MRS 1523
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