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Varenicline-d4

CAS No. : 2183239-01-0

Biological Activity：Varenicline-d4 is deuterium labeled Varenicline. Varenicline (CP 526555) is a potent partial agonist for α4β2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 μM. Varenicline is a full agonist for α3β4 and α7 nAChRs with EC50 values of 55 μM and 18 μM, respectively. Varenicline is a nicotinic ligand based on the structure of cytisine, has the potential for smoking cessation treatment^[2].

Research Area：Neurological Disease

Targets：nAChR

Related Small Molecules:Spinosad;Pyrantel;NS 9283;Myosmine-d4;Benzethonium chloride;Dihydro-β-erythroidine;A-867744;Catestatin;Asoxime dichloride;α7 nAchR-JAK2-STAT3 agonist 1;AR-R17779 hydrochloride;Mecamylamine hydrochloride;Tropisetron;Zolunicant;S16961;NS3861;(±)-Anatoxin A fumarate;Oxantel;PHA-543613 dihydrochloride;(S)-Dinotefuran;Nelonicline citrate;Coclaurine;Cytisinicline;NS 1738;Asoxime-d4 dichloride;(R)-(+)-Anatabine;nAChR modulator-1;BNC210

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