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Regorafénib N-oxyde (M2)
CAS No. : 835621-11-9
Biological Activity：Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.
Research Area：Cancer
Targets：Drug Metabolite|PDGFR
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Metabolism/Protease Compound Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;Angiogenesis-Related Compound Library;Drug Metabolite Library;
Related Small Molecules:Nicotinamide N-oxide;4-Hydroxyphenylbutazone;Henatinib;Ampyrone;Resveratrol-3-O-sulfate sodium;Sonidegib metabolite M48;Flumatinib mesylate;IHMT-TRK-284;Isonicotinic acid;PDGFRα/FLT3-ITD-IN-2;Cycloguanil hydrochloride;PP58;Hydroxytanshinone IIA;Chiauranib;Zeteletinib;ENMD-2076 Tartrate;Endoxifen
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