For research use only. We do not sell to patients.
ROCK2-IN-5
Biological Activity：ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation.
Research Area：Neurological Disease
Targets：ROCK
Related Small Molecules:Ripasudil free base;PF-4950834;ROCK-IN-4;GSK-25;AT13148;LX7101;Y-27632 dihydrochloride;RKI-1447;AS1892802;SB-772077B dihydrochloride;BDP5290;Fasudil;3-(4-Pyridyl)indole;GSK429286A;Verosudil;CRT0066854;H-1152 dihydrochloride;Cotosudil;ZINC00881524;Hydroxyfasudil hydrochloride;HA-100 hydrochloride;Thiazovivin;Rho-Kinase-IN-1;Y-33075;BAY-549
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Structurally and synthetically diverse biologically active compounds；
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