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VU0071063
CAS No. : 333415-38-6
Biological Activity:VU0071063 is a potent and specific Kir6.2/SUR1 opener (EC50=7.44 μM) and can be used for investigating Kir6.2/SUR1 expressed in the pancreas and brain. VU0071063 inhibits insulin secretion by inducing hyperpolarization of β-cell membrane potential. VU0071063 chemotype has a very steep structure-activity relationships[2].
Research Area:Neurological Disease|Others
Targets:Potassium Channel
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