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Amodiaquine dihydrochloride
CAS No. : 69-44-3
Biological Activity：Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor with a Ki of 18.6 nM. Amodiaquine dihydrochloride is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[2][3][4][5].
Research Area：Infection|Inflammation/Immunology|Neurological Disease
Targets：Parasite|Histone Methyltransferase
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Histone Modification Research Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;NMPA-Approved Drug Library;Pyroptosis Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Blood Cancer Compound Library;Antiparasitic Compound library;Targeted Diversity Library;Children’s Drug Library;Human Metabolite Library;Nuclear Receptor Compound Library;
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