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Ogerin
CAS No. : 1309198-71-7
Biological Activity：Ogerin is a selective GPR68 positive aliasing modulator (PAM) (pEC50=6.83) with a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-β-induced myofibroblast differentiation of fibroblasts from multiple organ systems. Ogerin can be used in the studies of fibrotic diseases and neurological disorders[2].
Research Area：Neurological Disease
Targets：GPR68
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Chemical Probe Library;Targeted Diversity Library;
Related Small Molecules:MS48107
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