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Hydralazine hydrochloride
CAS No. : 304-20-1
Biological Activity：Hydralazine hydrochloride is a orally active antihypertensive agent, reduces peripheral resistance directly by relaxing the smooth muscle cell layer in arterial vessel. Hydralazine hydrochloride has antioxidant activity, as well as inhibits ROS release and O2·- generation with an IC50 value of 9.53 mM and 1.19 mM, respectively[2].
Research Area：Cardiovascular Disease
Targets：HIF/HIF Prolyl-Hydroxylase
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Cancer Metabolism Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;
Related Small Molecules:TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;AKBA;LW6;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;HIF-1/2α-IN-1;Roxadustat;Daprodustat;Acetylarenobufagin;Zifcasiran;Acriflavine hydrochloride;BAY 87-2243;PHD-1-IN-1;PT-2385;ZINC13466751;(Rac)-Dencichine;Enarodustat;HIF-2α-IN-6;ENMD-1198
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