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PI3K/Akt/CREB activator 1
CAS No. : 2708177-73-3
Biological Activity:PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD).
Research Area:Neurological Disease
Targets:Epigenetic Reader Domain|Akt|PI3K
Related Small Molecules:Akt/NF-κB/JNK-IN-1;RVX-297;Umbralisib hydrochloride;BRD4 Inhibitor-19;Topoisomerase I/II inhibitor 3;UNC6349 (Ket2);Cyclovirobuxine D;Curcumin;Rigosertib sodium;GSK6853;Tenalisib R Enantiomer;GSK4028;AKTide-2T;PI3kδ inhibitor 1;Sennidin A;PI3K/VEGFR2-IN-1;SR-0813;Inobrodib;MS98;PP2A Cancerous-IN-1;Apabetalone;OF-1;I-CBP112;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;A-485;PI3Kα-IN-8;PLX51107
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