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Nefazodone hydrochloride
CAS No. : 82752-99-6
Biological Activity：Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A (Ki=5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake (IC50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity[2].
Research Area：Neurological Disease|Endocrinology
Targets：Adrenergic Receptor|5-HT Receptor
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;FDA-Approved Drug Library;CNS-Penetrant Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;Neurotransmitter Receptor Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Alzheimer’s Disease Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Antidepressant Compound Library;5-HT Receptor Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:F 13714;Mosapride-d5;Todralazine;ARC 239 dihydrochloride;Nuciferine;Yohimbine;Glaucine;Salbutamol;Renzapride;BI-167107;LY 344864 racemate;Harmine hydrochloride;Talibegron hydrochloride;Valerenic acid;Arotinolol;SR59230A;Melitracen-d6 hydrochloride;WAY-100635
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