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Izilendustat hydrochloride

CAS No. : 1303513-80-5

Biological Activity：Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1)^[2]^[3].

Research Area：Cancer|Inflammation/Immunology

Targets：HIF/HIF Prolyl-Hydroxylase

Related Small Molecules:TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;AKBA;LW6;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;HIF-1/2α-IN-1;Roxadustat;Daprodustat;Acetylarenobufagin;Zifcasiran;Acriflavine hydrochloride;BAY 87-2243;PHD-1-IN-1;PT-2385;ZINC13466751;(Rac)-Dencichine;Enarodustat;HIF-2α-IN-6;ENMD-1198

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