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Quercitrin

CAS No. : 522-12-3

Biological Activity：Quercitrin is a natural compound found in widespread with a potential anti-inflammation effect that is used to treat heart and vascular conditions.
IC50 value:
Target:
In vitro: There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. [1]
In vivo: ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. [2]

Research Area：Inflammation/Immunology

Targets：Autophagy|Reactive Oxygen Species|Ribosomal S6 Kinase (RSK)

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