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Bisacodyl
CAS No. : 603-50-9
Biological Activity：Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect.
Research Area：Metabolic Disease|Cancer
Targets：Opioid Receptor|Dopamine Transporter
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