MPP+ iodide

For research use only. We do not sell to patients.

MPP+ iodide

CAS No. : 36913-39-0

Biological Activity:MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson’s disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[2].

Research Area:Neurological Disease

Targets:Mitochondrial Metabolism

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Glycolysis Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;Glucose Metabolism Compound Library;Cuproptosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:MitoTam bromide, hydrobromide;MitoTEMPO hydrate;NL-1;Thiabendazole-d4;D-Histidine;Mito-apocynin (C2);Fumarate hydratase-IN-2 sodium salt;Schaftoside;Daidzin;Azemiglitazone;Tempo;Idebenone;Menadiol;CTPI-2;Senecionine acetate;Antimalarial agent 14;Mito-apocynin (C11);OXPHOS-IN-1;Mitochondrial respiration-IN-1 hydrobromide;Tubulin/HDAC-IN-1;Clidanac;IMT1;Nonactin;RYL-552;DX2-201;MSDC 0160

Trending products:Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

  • MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use;
  • Structurally and synthetically diverse biologically active compounds;
  •  roduct quality is the key to our success and we take pride in offering only the highest-grade products.;
  • We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.;
  • Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.;
  • Structurally and synthetically diverse biologically active compounds;

  • Customized order volume ranging from milligrams to kilograms scale;
  • We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

50K Diversity Library
Top Publications Citing Use of MCE Products
Recombinant Proteins
magnetic-beads