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(E)-SIS3
CAS No. : 521984-48-5
Biological Activity：(E)-SIS3 is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation. (E)-SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
Research Area：Inflammation/Immunology
Targets：TGF-beta/Smad
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Targeted Diversity Library;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:TGFβ-IN-2;SRI-011381;Ponsegromab;Isoviolanthin;ALK5-IN-32;Asiaticoside;Halofuginone hydrobromide;ALK5-IN-28;Oxymatrine;Trabedersen;CCT365623 hydrochloride;Butaprost;Disitertide TFA;ALK5-IN-34;Alantolactone;Chebulinic acid;R-268712;Mongersen;EMT inhibitor-1;IDE 2;10,11-Dehydrocurvularin
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