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Ivabradine hydrochloride
CAS No. : 148849-67-6
Biological Activity:Ivabradine hydrochloride is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine hydrochloride reduces dose-dependently heart rate without modification of blood pressure. Ivabradine hydrochloride shows anticonvulsant, anti-ischaemic and anti-anginal activity[2][3][4].
Research Area:Cardiovascular Disease|Endocrinology|Cancer
Targets:HCN Channel
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Anti-Cardiovascular Disease Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Neuroprotective Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Rare Diseases Drug Library;Children’s Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;
Related Small Molecules:Cilobradine hydrochloride;Zatebradine hydrochloride;ZD7288;ZD 7288-d3
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