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FBPase-IN-1
CAS No. : 20362-54-3
Biological Activity：FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase.
Research Area：Metabolic Disease
Targets：FBPase
Related Small Molecules:FBPase-1 inhibitor-1;FBPase-IN-2;Managlinat dialanetil;MB05032
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