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GR 64349
CAS No. : 137593-52-3
Biological Activity:GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively[2].
Research Area:Neurological Disease
Targets:Neurokinin Receptor
Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy Netupitant;SB-222200;Senktide;GR 87389;Hemokinin 1, human;Neurokinin A TFA;Imnopitant dihydrochloride;[Glp6] Substance P (6-11);[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA;[Pro9]-Substance P;Befetupitant;Hemokinin 1 (mouse);Substance P Receptor Antagonist 1;(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B;Substance P (1-9);(D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P;Substance P-Gly-Lys-Arg
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