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Cathepsin C-IN-5
CAS No. : 2825567-97-1
Biological Activity：Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 µM, >5 µM, >5 µM, >5 µM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity.
Research Area：Inflammation/Immunology
Targets：Cathepsin
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Orally Active Compound Library;Angiogenesis-Related Compound Library;
Related Small Molecules:Calpeptin;Cathepsin G Inhibitor I;Gly-Phe-β-naphthylamide;Z-FY-CHO;Balicatib;Cathepsin D and E FRET Substrate;N-CBZ-Phe-Arg-AMC TFA;LV-320;Z-LVG-CHN2;ONO-5334;VBY-825;L-873724;Z-WEHD-FMK;Odanacatib;Atg4B-IN-2;Cysteine Protease inhibitor;KGP94;E-64;Cathepsin L-IN-2;LmCPB-IN-1;MK-0674;MIV-247;Aurantiamide acetate;SID 26681509;ALLM;LY 3000328;Cathepsin C-IN-3;K777
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