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Canakinumab
CAS No. : 914613-48-2
Biological Activity：Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC50 values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin[2].
Research Area：Inflammation/Immunology
Targets：Interleukin Related
Related Small Molecules:AX-024;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;Raleukin;Ossirene;VGX-1027;RCGD423;Clazakizumab;Reslizumab;Gamma-glutamylcysteine TFA;Tyrphostin A1;Interleukin (IL)-6 Receptor;Satralizumab;Sirukumab;Siltuximab
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