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SB 202190
CAS No. : 152121-30-7
Biological Activity：SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[2]. SB202190 induces autophagy[3].
Research Area：Cancer|Neurological Disease
Targets：Autophagy|p38 MAPK|Apoptosis
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Neurodegenerative Disease-related Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium
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