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KU-177
CAS No. : 1160952-43-1
Biological Activity：KU-177 is a potent inhibitor of Hsp90 ATPase homologue 1 (Aha1), ablates Aha1-driven enhancement of Hsp90-dependent tau aggregation. KU-177 also disrupts Aha1/Hsp90 interactions (IC50=4.08 μM) without inhibition of Hsp90’s ATPase activity. KU-177 can be used for tauopathies research[2].
Research Area：Cancer
Targets：HSP
Related Small Molecules:6BrCaQ;116-9e;Paeoniflorin;HDAC/HSP90-IN-4;Debio 0932;MKT-077;Ethoxyquin;Cemdomespib;Apatorsen;HS-131;CH5138303;Pimitespib;NCT-58;MPC-0767;Retaspimycin;BOLD-100;Onalespib;HSP90-IN-12;Palmitic acid-1-13C;Palmitic acid-d3;Feretoside;Palmitic acid-d9;Palmitic acid-13C2;Gamitrinib TPP;JG-98;Gedunin;Rocaglamide;Palmitic acid-13C sodium;AMP-PCP
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