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Cucurbitacin D
CAS No. : 3877-86-9
Biological Activity:Cucurbitacin D is an active component in Trichosanthes kirilowii, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity.
Research Area:Cancer
Targets:HSP
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Lipid Compound Library;Endoplasmic Reticulum Stress Compound Library;Medicine Food Homology Compound Library;Terpenoids Library;Pyroptosis Compound Library;Cytoskeleton Compound Library;Traditional Chinese Medicine Active Compound Library;Food-Sourced Compound Library ;Anti-Cancer Natural Product Library;Protein-protein Interaction Inhibitor Library;Plant-Sourced Natural Product Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
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