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Pentamidine isethionate

CAS No. : 140-64-7

Biological Activity：Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC₅₀ of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities^[2][3][4].

Research Area：Infection|Cancer

Targets：Parasite|Fungal|Bacterial|Antibiotic|Phosphatase

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;Oxygen Sensing Compound Library;Antifungal Compound Library;Antibacterial Compound Library;Anti-COVID-19 Compound Library; FDA Approved & Pharmacopeial Drug Library;Antibiotics Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Phosphatase Inhibitor Library;Antiparasitic Compound library;Rare Diseases Drug Library;Children’s Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;

Related Small Molecules:Antifungal agent 20;(+)-Isopulegol;Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Debneyol;Leucomycin;Isouvaretin;Haloprogin;GNF362;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28

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