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CID44216842

CAS No. : 1222513-26-9

Biological Activity：CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC₅₀s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC₅₀s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe.

Research Area：Cancer

Targets：Ras

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Ferroptosis Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;

Related Small Molecules:Deltarasin hydrochloride;ZINC09659342;KRAS G12C inhibitor 56;CCG-232601;KRAS G12D inhibitor 14;1A-116;KRAS G12D inhibitor 10;KRAS G12C inhibitor 20;KRAS G12C inhibitor 24;RM-018;KRAS G12C inhibitor 14;APS6-45;6H05;KRpep-2d TFA;KRAS G12C inhibitor 33;KRAS G12C inhibitor 53;K-Ras-IN-1;KRAS G12C inhibitor 41;KRAS G12C inhibitor 26;KRAS G12C inhibitor 16;KRAS inhibitor-11;SOS1-IN-13;BQU57;ZCL278;Digeranyl bisphosphonate;KRAS inhibitor-7;SOS1 activator 1;KRAS inhibitor-14;SAH-SOS1A

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