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Topotecan-d5
CAS No. : 1133355-98-2
Biological Activity：Topotecan-d5 is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC50 values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95±0.24 μM of GSCs-U87[2].
Research Area：Cancer
Targets：Topoisomerase|Autophagy
Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Topoisomerase II inhibitor 8;FLT3-IN-13;TP3011;TAS-103 dihydrochloride;Rebeccamycin;AZD5099;TP0480066;Topoisomerase I inhibitor 4;Camptothecin;Corydamine;SW044248;9-Hydroxyellipticine hydrochloride;Flumequine-13C3;Trovafloxacin mesylate;Topoisomerase II inhibitor 12;Topoisomerase I inhibitor 3;Berberine sulfate;Betulinic acid;Hycanthone;Niranthin
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