Peiminine

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Peiminine

CAS No. : 18059-10-4

Biological Activity:Peiminine(Verticinone; Raddeanine) is a natural compound with anti-inflammatory activity.
IC50 value:
Target:
Peiminine and DXS significantly reduced alveolar inflammation and pulmonary interstitial inflammation in rats with bleomycin-induced lung injury. peiminine inhibits lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury, by reducing circulating IFN-γ levels and inhibiting signal transduction pathways involving TGF-β, CTGF, ERK1/2, NF-κB and FasL.

Research Area:Inflammation/Immunology|Cancer

Targets:Autophagy

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