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Amelparib
CAS No. : 1227156-72-0
Biological Activity:Amelparib is a potent, orally active, and water-soluble inhibitor of PARP-1. Amelparib inhibits PARP-1 activity (IC50 =18.5 nmol/L) and cellular PAR formation (IC50 =10.7 nmol/L) in the nanomolar range. Amelparib is a potential neuroprotective agent. Amelparib has the potential for the research of acute ischaemic stroke.
Research Area:Neurological Disease|Cardiovascular Disease
Targets:PARP
Related Small Molecules:Rucaparib monocamsylate;AZD-2461;Senaparib;Dehydrocorydaline;Rucaparib hydrochloride;Niraparib tosylate;G007-LK;PROTAC PARP1 degrader;UPF 1069;DP-C-4;Δ5-Avenasterol-d4;PARP14 inhibitor H10;CEP-9722;E7449;PARP1-IN-11;PI-1840;5,7-Dihydroxychromone;PARP-1/2-IN-1;(8R,9S)-Talazoparib;3-Aminobenzamide;PARP1-IN-12;PARP-1-IN-2;BRCA1-IN-1;NMS-P118;VPC-70063;G244-LM
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