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SAR407899
CAS No. : 923359-38-0
Biological Activity：SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation.
Research Area：Metabolic Disease
Targets：ROCK
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Reprogramming Compound Library;Anti-diabetic Compound Library;Anti-COVID-19 Compound Library;Cytoskeleton Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Ripasudil free base;PF-4950834;ROCK-IN-4;GSK-25;AT13148;LX7101;Y-27632 dihydrochloride;RKI-1447;AS1892802;SB-772077B dihydrochloride;BDP5290;Fasudil;3-(4-Pyridyl)indole;GSK429286A;Verosudil;CRT0066854;H-1152 dihydrochloride;ROCK2-IN-5;Cotosudil;ZINC00881524;Hydroxyfasudil hydrochloride;HA-100 hydrochloride;Thiazovivin;Rho-Kinase-IN-1;Y-33075;BAY-549
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